Styx played the Spartanburg Memorial Auditorium on April 14, 2010. The setlist included:
Borrowed Time / Superstars / Mr. Roboto / Rockin' The Paradise / Pieces of Eight
The Grand Illusion
Too Much Time on My Hands
Lady
Lorelei
Snowblind
I Am the Walrus (The Beatles cover)
Boat on the River
Crystal Ball
Suite Madame Blue
Fooling Yourself (The Angry Young Man)
Blue Collar Man (Long Nights)
Miss America
Come Sail Away
Encore:Coming of Age (Damn Yankees cover)
Renegade